Novo Nordisk nach Split WKN: A3EU6F ISIN: DK0062498333 Kürzel: NOV Forum: Aktien User: Coronaprofiteur
EFX was generally well tolerated, with a safety profile consistent with previous trials. The most frequent adverse events were mild to moderate gastrointestinal events (e.g., diarrhea, nausea, increased appetite), which occurred at similar rates in the 28mg and 50mg groups. The rate of treatment discontinuation was similar for both doses but was greater than that for placebo. A small reduction in bone mineral density compared with placebo was observed after 96 weeks of EFX treatment. The relevance of this observation remains to be determined, as poor or declining bone health is common in adults with MASH. https://www.globenewswire.com/news-release/2025/08/14/3134001/0/en/Akero-Therapeutics-Announces-Lancet-Publication-of-the-Phase-2b-HARMONY-Clinical-Trial-Demonstrating-96-Weeks-Treatment-with-EFX-Reduced-Liver-Fibrosis-in-Patients-with-Pre-cirrhot.html
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