PACIFIC BIOSCIENCES OF CALIFORNIA WKN: A1C3EQ ISIN: US69404D1081 Kürzel: PACB Forum: Aktien Thema: Hauptdiskussion

“The new Sequel IIe System represents the next advance in our technology, and makes HiFi sequencing accessible to any project where high accuracy, long read lengths, and affordability matter,” said Christian Henry, Chief Executive Officer of Pacific Biosciences. “Prior to HiFi sequencing, researchers used multiple technologies and complex analysis methods in order to obtain results comparable to HiFi data. With the Sequel IIe System, it’s now simple to produce HiFi data directly — and scientists can feel confident using only one technology to power their genetic discoveries.”

https://enlightenbio.blog/2020/10/05/pacific-biosciences-launches-the-sequel-iie-system-to-accelerate-adoption-of-highly-accurate-hifi-sequencing/

In this paper, PacBio showed that they can generate very high quality PacBio sequencing by reading the same molecule multiple times (~10 times on average) rather than comparing 10 separate reads together. This means that they end up with individual PacBio CCS reads with roughly the same error rate as Illumina reads, but which are much longer than Illumina reads.

https://www.genengnews.com/insights/dna-sequencing-accuracy-comes-a-long-way/

https://bioengineeringcommunity.nature.com/posts/52218-highly-accurate-long-read-dna-sequencing-improves-analysis-of-a-human-genome

https://www.nature.com/articles/s41588-019-0559-8

https://mobile.twi.tter.com/sequegenics/status/1287876070700511234

https://searchstorage.techtarget.com/news/252487605/NetApp-Data-Fabric-aids-manufacturers-gene-sequencing-gear?amp=1&__twitter_impression=true

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