Sixth Wave Innovations Forum: Community User: Ertan26
Kommentare 1.453
g
grubbel,
14.04.2021 15:55 Uhr
0
Sixth Wave Demonstrates Colorimetric Detection
of SARS-CoV-2 utilizing AMIPs™
Halifax, Nova Scotia – (April 13, 2021) – Sixth Wave Innovations Inc. (CSE:SIXW) (OTCQB:ATURF) (FSE:AHUH) (“Sixth Wave”, “SIXW” or the “Company”) is pleased to announce that it has successfully demonstrated colorimetric detection of SARS-CoV-2, the virus that causes COVID-19 (the “Virus”) utilizing the Company’s patent pending Accelerated Molecular Imprinted Polymers (“AMIPs™”) technology.
Colorimetric detection is a method of identifying the presence of a target substance within a test sample by means of a color reagent. When successfully applied, the activation of the reagent indicates the presence of the target substance.
The demonstration, performed by way of a simulated synthetic enzyme-linked immunosorbent assay (“ELISA”) test, is represented by the following microscopic images:
L
Locke_Der_Boss,
14.04.2021 15:10 Uhr
0
Oh man, die news sollen endlich mal was liefern
g
grubbel,
12.04.2021 8:16 Uhr
0
Nein. Man darf gespannt sein. Irgendwelche Umsatzzahlen wären schön ..
F
Fulltrader,
09.04.2021 11:10 Uhr
0
Hatte ich auch gelesen ,wen einer 6 Millionen investiert muss er sich ja einiges von den Produkten versprechen ,das macht man nicht einfach so .
g
grubbel,
09.04.2021 10:24 Uhr
0
https://sixthwave.com/sixth-wave-announces-closing-of-6000000-private-placement/
R
Relaxed01,
18.03.2021 14:15 Uhr
0
https://the.marketherald.ca/announcements/sixth-wave-innovations-inc-ordinary-shares-2021-03-18-7940546403625887/
R
Relaxed01,
18.03.2021 14:10 Uhr
0
https://themarketherald.ca/announcements/sixth-wave-innovations-inc-ordinary-shares-2021-03-18-7940546403625887/
L
Locke_Der_Boss,
15.03.2021 17:19 Uhr
0
Ja, Hauptsache da kommt Kohle rein 😁
F
Fulltrader,
15.03.2021 14:45 Uhr
0
Leider nicht ,denk aber das die Corona Situation das ganze verlangsamt hat .Das erste Affinity System ist ja gerade bei einem Cannabiskunden zum Test .Ob die Masken oder nur die Testsysteme eine Zulassung brauchen keine Ahnung!Ich bin aber trotzdem guter Dinge .Ich hoffe das bis Sommer endlich Umsatz in irgendeiner Form gemacht wird .Mit was ist mir eigentlich egal.Wir brauchen Geduld
g
grubbel,
15.03.2021 14:20 Uhr
0
Eigentlich sollten Anfang 2021 Umsätze generiert werden, jetzt gibt es noch nicht einmal einen Antrag bei der FDA. Kennt jemand eine unabhängige Quelle zur Einschätzung der bisherigen Ergebnisse?
L
Locke_Der_Boss,
15.03.2021 8:13 Uhr
0
Das dauert noch bis alle geimpft sind 🤭
F
Fulltrader,
14.03.2021 14:40 Uhr
0
War schon schlechter ,aber die müssen jetzt mal die Tests Abschliessen und den Antrag bei der FDA stellen für die Zulassung .Dann sehen wir auch die Rakete!
L
Locke_Der_Boss,
12.03.2021 19:39 Uhr
0
Ganz gut die letzten Tage
g
grubbel,
10.03.2021 14:46 Uhr
0
Sixth Wave’s Polymer Imprint Detects
SARS-CoV-2 During Initial Testing™
Halifax, Nova Scotia – (March 9, 2021) – Sixth Wave Innovations Inc. (CSE: SIXW) (OTCQB: ATURF) (FSE: AHUH) (“Sixth Wave”, “SIXW” or the “Company”) is pleased to announce preliminary results evidencing the binding and detection capabilities of its Accelerated Molecular Imprinted Polymers (“AMIPs™”) technology for the rapid detection of SARS-CoV-2, the virus that causes COVID-19 (the “Virus”).
As previously reported, SIXW recently produced a first-generation molecular imprint of the Virus (the “Imprint”), thereafter commencing a series of validation tests to quantify the effectiveness of the imprinting process (the “Validation Testing”). The initial steps of Validation Testing are to characterize the virus template, the polymer as well as the imprints of the COVID-19 virus in the AMIPs™.
Using this feedback, and adjusting for parameters impacting the accuracy and speed of detection, successive iterations of the Imprint will continue to be derived. The goal of this process is to generate a precise master imprint, capable of identifying the Virus with exceptional accuracy (the “Definitive Imprint”). The successful proof-of-concept allows for testing of different parameters and features for product development and prototyping. Ultimately, the goal will be to have an AMIP™ capable of being deployed in a wide range of applications, including smart-clothing and PPE applications, airborne sensors, breathalyzers, ELISA-based technologies, cartridge/lateral flow designs, and others. For more information on AMIPs, the Imprint, Validation Testing, patent applications, and the Company’s planned path to production, please see SIXW Press Release dated February 9, 2021.
Announcement of Successful Detection of the Virus
The first stage of the now in-progress Validation Testing program comprises analyses to confirm that the Imprint is capable of effectively binding to the target Virus and being detected by a sensor system. To accomplish this, SIXW used a variety of analytical tools typical of validating and quantifying binding and detection of viruses, including Atomic Force Microscopy (“AFM”) and Quartz Crystal Microbalance (“QCM”). The Company continues to benefit from its engagement with the University of Alberta (“UofA”) researchers and utilizing UofA’s advanced laboratory and associated assessment tools.
Sixth Wave is pleased to report that initial detection has now been successfully achieved via AFM / QCM analysis which has provided positive results indicating that the virus is attracted to the AMIPs™ polymer at detectable levels.
“This is a considerable step forward on the path to product validation,” said Dr. Jon Gluckman, President and CEO of Sixth Wave. “As we have already demonstrated the ability to produce an Imprint on reasonably short turnaround, this most recent testing establishes that the polymer works – it captures the virus at detectable levels. We’re now proceeding to create additional fully functional sensors using Quartz Crystal Microbalances (QCM) to determine the sensitivity, selectivity, capture rates, and speed of detection. These data points will help guide future iterations of the AMIPs™ polymer to meet the performance criteria required by regulatory agencies (such as Health Canada and the FDA) and to produce innovative and affordable product to address the unmet needs of the market for rapid test products.”
“We’ve created dozens of AMIPs™ prototype sensors to develop our proof-of-concept. Each sensor has led to new insight into the refinement of methods and protocols to continuously advance our sensors.” said Dr. Garrett Kraft, Sixth Wave’s Senior Scientist for AMIPs development. “Capturing the COVID-19 virus is a major victory in our development path and provides a solid indicator that we are on the right path to bringing the AMIPs™ technology to market”.
The Company is not making any express or implied claims that its product has the ability to eliminate, cure, contain, or detect, at a commercial level, COVID-19 (or SARS-2 coronavirus) at this ****
Background & Next Steps
Preliminary results using AFM and QCM at the UofA facility give evidence to the binding of the Virus into the associated imprinted cavities of the polymer. Pre- and post-exposure changes in frequency response of the QCM empirically demonstrate the ability of AMIPs™ to detect the Virus.
Now that initial Imprint and binding analyses have been completed, the Company will pursue remaining Validation Testing in order to optimize the existing AMIPs™ configuration, with a view to establishing the Definitive Imprint. Forthcoming test work, utilizing AFM/QCM and possibly other techniques, will include optimization of the Imprint for sensitivity, selectivity, capture rates and speed of detection. As part of the optimization process, the Company intends to perform additional testing to validate the ability of the AMIPs™ to capture and detect the mutations and variants of the Virus.
Test work at the UofA laboratories is progressing under the direction of Sixth Wave Senior Scientist Dr. Garrett Kraft, in cooperation with Dr. Michael J. Serpe (UofA Department of Chemistry) and Dr. Michael Joyce (UofA Department of Medical Microbiology), to achieve proof-of-concept for the AMIPs™ virus rapid detection platform. The relationship with UofA allows for access to the Virus and other pathogens, as well as access to a variety of advanced analytical equipment needed for this development.
As previously reported, SIXW has filed two patents regarding the AMIPs platform, and has established a collaborative research team including other world-renowned scientist and research centers.
For more information on the AMIPs™ and associated molecular imprinting technology, please visit: https://www.amips.com
F
Fulltrader,
09.03.2021 16:29 Uhr
0
Wir brauchen nur Geduld auch wen es schwer fällt
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