REDHILL B.S.ADR 10/IL-,01 Forum: Community User: MeisterYoda1

@Schnorps mir geht es ähnlich wie dir. Glücksgefühle kommen hier so einfach keine mehr auf. Aber vielleicht betreiben sie jetzt mal ein wenig Kursmarketing

hospital more quickly,” said Danielle T. Abramson, Ph.D., SVP Global Head of Intellectual Property at RedHill. “This latest patent not only adds to the strong existing IP suite for opaganib but further provides for coverage for the patients most likely to benefit from its potential to treat people with COVID-19, pneumonia and who require supplemental oxygen – a key patient sub-group for which opaganib has already demonstrated nominally statistically significant efficacy in a large Phase 2/3 clinical trial.” Recent shifts in international and governmental policy, research, and funding have directed focus toward development of broad-acting, host-pathway targeting antivirals with activity against a range of viruses with the potential to prevent future viral pandemics. RedHill’s novel, broad-acting, host- directed antiviral, opaganib, has shown, despite three years of continual viral mutation, encouraging signs of its potential against the COVID-19-causing SARS-CoV-2 variants, as well as additional data suggesting potential activity against various other viruses, including influenza A. Opaganib’s suggested host-directed mechanism of action was recently described in a manuscript entitled "Recent Progress in the Development of Opaganib for the Treatment of COVID-19" published in the journal Drug Design, Development and Therapy in July 2022. The paper outlines opaganib's multi-faceted potential to: inhibit multiple pathways, induce autophagy and apoptosis, and disrupt the viral RTC (replication-transcription complex) through simultaneous inhibition of three sphingolipid- metabolizing enzymes in human cells (SK2, DES1 and GCS). These mechanisms support the hypothesis of broad antiviral effect and attenuation of multi-organ dysfunction in COVID-19 patients. Moreover, because of its host-directed targeting, opaganib is unlikely to encounter viral resistance due to mutation, which may be a problem for direct-acting antivirals. Late-stage development of opaganib is ongoing pending Phase 3 trial design regulatory approvals and securing of external funding

RDHL) (“RedHill” or the “Company”), a specialty biopharmaceutical company, today announced the granting by the United States Patent and Trademark Office (USPTO) of a further method of use patent that protects the administration of opaganib1 for the inhibition of a disease caused by a coronavirus in a subgroup population of patients requiring a fraction of inspired oxygen (FiO2) up to and including 60% at baseline, adding to the existing strong patent suite covering opaganib. The new patent, expiring in 2041, titled “Sphingosine Kinase 2 Inhibitor for Treating Coronavirus Infection in Moderately Severe Patients with Pneumonia”, protects the results from a post-hoc analysis from the global Phase 2/3 study in hospitalized patients with COVID-19 pneumonia (NCT04467840). This analysis of 251 study participants requiring a FiO2 up to and including 60% at baseline (54% of study participants) demonstrated that treatment with oral opaganib resulted in a 62% reduction in mortality, improved outcomes in time to room air and median time to hospital discharge, and a reduced likelihood of intubation and mechanical ventilation in this large group of hospitalized, moderately severe COVID-19 patients. “COVID-19 continues to challenge public health providers and patients across the world and continues to be the cause of significant mortality and morbidity. Patients with moderately severe COVID-19 and pneumonia face a lack of treatment options capable of reducing mortality and getting patients out of

RedHill's Oral Broad-Acting Antiviral, Opaganib, Granted New COVID-19 Treatment Patent https://www.prnewswire.com/news-releases/redhills-oral-broad-acting-antiviral-opaganib-granted-new-covid-19-treatment-patent-301653409.html

RedHill Biopharma (Nasdaq: RDHL) today announced the granting by the United States Patent and Trademark Office (USPTO) of a further method of use patent that protects the administration of opaganib for the inhibition of a disease caused by a coronavirus in a subgroup population of patients requiring a fraction of inspired oxygen (FiO2) up to and including 60% at baseline, adding to the existing strong patent suite covering opaganib. · USPTO grants new method of use patent for the inhibition of a disease caused by a coronavirus in patients having pneumonia and receiving supplemental oxygen at a fraction of inspired oxygen (FiO2) up to and including 60% · Previous variant-agnostic efficacy data for opaganib, an investigational new drug for COVID-19 disease and several other viral diseases, highlights its promising profile as a broad acting, host-directed candidate therapy for pandemic preparedness · Development of opaganib for moderately severe COVID-19 patients is ongoing, including ongoing and planned pandemic preparedness research collaborations with US governmental agencies, pivotal Phase 3 trial design and regulatory clearances, and securing of external non-dilutive funding “COVID-19 continues to challenge public health providers and patients across the world and continues to be the cause of significant mortality and morbidity. Patients with moderately severe COVID-19 and pneumonia face a lack of treatment options capable of reducing mortality and getting patients out of hospital more quickly,” said Danielle T. Abramson, Ph.D., SVP Global Head of Intellectual Property at RedHill. “This latest patent not only adds to the strong existing IP suite for opaganib but further provides for coverage for the patients most likely to benefit from its potential to treat people with COVID-19, pneumonia and who require supplemental oxygen – a key patient sub-group for which opaganib has already demonstrated nominally statistically significant efficacy in a large Phase 2/3 clinical trial.”

Naja. Wieder eine Nachricht mehr. Meine Euphorie hält sich bei den riesigen Buchverlusten aber sehr in Grenzen. Anders ausgedrückt. Was bringt uns diese Erkenntnis? Es steht ja auch klar drin das die Entwicklung von Opagsnib weiterhin nicht abgeschlossen ist, das das Design der Phase-3 Studie erst einmal genehmigt werden muss und die Finanzierung noch aussteht.... Zumindest wollen sie die Finanzmittel ohne "Verwässerung " beschaffen... Naja... Bei meinen 90% Minus lese ich das inzwischen ohne innere Regung...

$RDHL- Opaganib, RedHills oral verabreichtes breit wirksames Virostatikum, erhält neues Patent für die Behandlung von COVID-19

So, so, das Management war es also 😂😂😂 ein wortreicher Meister der Selbstrechtfertigung 🙈 🙉🙊 (und der Selbsttäuschung), der @quovadiskurs... Als wenn ich nicht genau vor diesem Management gewarnt hätte (neben der mickrigen Pipeline natürlich - das waren die beiden Kritikpunkte und jeder für sich genommen reicht schon vollkommen, von diesem Unternehmen Abstand zu nehmen). Mir egal; solche Charaktere rennen ohnehin immer geradewegs gegen den nächsten Baum, da ist nix zu machen. Und immer ist der Baum schuld, weil er an der falschen Stelle gestanden hat.

In so einer Situation vom aktuellen Kurs mehr als 100% zulegen ist unmöglich...nach dem folgenden Split ist das Ding noch lange nicht gestorben - Redhill wird weiter saugen bis tatsächlich nichtsmehr an Aktienwert vorhanden ist. Hier ist auch wie schon mehrfach erwähnt die Fa. Neovacs ein Musterbeispiel für das was noch kommt

hab hier etwas interessantes gefunden: HCR hat die Lizenzgebühren für Movantik schon von Nektar 2020 erworben. Ist das, was jetzt geplant ist zur "Finanzgewinnung" eventuell eine Rückabwicklung? http://www.healthcareroyalty.com/portfolio-item/nektar-therapeutics/ https://www-healthcareroyalty-com.translate.goog/portfolio-item/nektar-therapeutics/?_x_tr_sch=http&_x_tr_sl=auto&_x_tr_tl=de&_x_tr_hl=de

Ich glaube nicht, dass vor dem 10. April ein rs kommen wird. Denn sie hätten nach dem 10. April nochmal 180 Tage Zeit um über 1 zu kommen

es wird der scheiss r/s kommen, wetten???? ganz ehrlich, dann ist es auch schon egal und ich lass das teil einfach liegen.

Das gibt ab 15:30 noch ne weiter Rutsche...

Also wird das „Spielchen“ noch mindestens bis zum 10.April 2023 so weiter gehen... Geduld haben oder raus gehen

Sie haben jetzt bis zum 10. April 2023 Zeit, wieder über einen Dollar zu kommen. Mittel dazu könnten sein: Endlich ein ordentliches Business zu betreiben oder einen Reverse Split durchzuführen. Mal sehen, für welche der beiden Optionen die sich entscheiden.